Endocrine Abstracts

Prevalence of hyperandrogenism (HA) and polycystic ovary syndrome (PCOS) in female to male transsexuals (FMT) is controversial. To known the prevalence of hyperandrogenism and PCOS in FMT, and their relation with insulin resistance (IR) and other cardiovascular risk factors (CVRF), we studied 77 Spanish consecutive FMT cases, the first ones who appeared in our Gender Unit between May 2007 and Dec 2008, aged 18–43 years. The subjects had never received hormonal treatment o...

Introduction: Different studies have published that testosterone therapy in men and women results in decreased HDL cholesterol and increased LDL cholesterol, and therefore an increased cardiovascular risk.Aims: To determine whether testosterone therapy has this effect on lipid parameters and markers of metabolic syndrome (MetSyn) in female-to-male transsexuals (FMT).Material and methods: We studied 50 FMT, aged 27.8±7.6 years,...

Moderately elevated body iron stores may be associated with several components of the metabolic syndrome (MetSyn). Elevated serum ferritin levels (Fer) independently predicted incident type 2 diabetes in prospective studies in apparently healthy men and women.Aims: To analyze the association between Fer and components of MetSyn in transsexuals before and after 2-year cross-sex treatment (CST).Methods: Before starting the CST in 90 ...